JAC1 targets YY1 mediated JWA/p38 MAPK signaling to inhibit proliferation and induce apoptosis in TNBC
Abstract Triple negative breast cancer (TNBC) is a type of breast cancer with poor prognosis, and has no ideal therapeutic target and ideal medicine.Downregulation of JWA is closely related to the poor overall survival in many cancers including g5210t-p90 TNBC.In this study, we reported at the first time that JWA gene activating compound 1 (JAC1) i